Cell Therapy and Gene Therapy Research and Development
Cell and gene therapy are similar fields of biomedical research aimed at treating genetic diseases and are often combined in treatment.
Cell therapy was introduced in the 1940’s during the first blood transfusion. It is performed by injecting whole live cells into the body, and has been used to treat cancers, hemophilia, leukemias, lymphomas, and immunodeficiencies.
Though similar, gene therapy is the use of genetic material to manipulate or alter a person’s genes in order to treat disease. Gene therapy has been around since the 1970’s and has been used to replace mutated, disease causing genes with healthy ones, inactivate disease causing genes that may not be functioning properly, and introducing new genes to fight off a disease.
Cell and gene therapy are often used in conjunction for better, more effective treatment of diseases.
Contract Laboratory gets many requests needing cell or gene therapy testing. Some recent examples include:
- Preclinical laboratory needed for gene enhanced cell therapy toxicology study in immunocompromised rats, cannulated jugular vein injection of gene enhanced cell therapy product. Standard 8 week toxicology study in 20 athmyic nude rats -Deadline for report is November, require start date of mid-august
- USA Preclinical Contract Research Organization CRO needed for preclinical proof of concept study: Stereotactic injection of 6-hydroxydopamine to lesion the striatum of mice and rats. Follow up with injection dopaminergic neuronal precursors for testing of a Parkinson’s disease cell therapy. The animals will need to be housed for an additional 18 weeks after transplantation with periodic behavioral assays including amphetamine-induced rotations, and a stepping test.
- USA GMP FDA Bioanalytical Laboratory needed for LAL or Pyrogen testing for cell therapy
- Microbiology laboratory needed to conduct microbial and fungal sterility testing and LAL endotoxin testing of our cell therapy product in Chicago.
Click here to view more of our Incoming cell and gene therapy Laboratory Test Requests
Are you a pharmaceutical, biopharmaceutical, life science, biotechnology or medical device company in need of a Contract Research Organization CRO for research and development of cell or gene therapy products? Submit a cell therapy or gene therapy Laboratory Test Requests
If you have question about Cell Therapy and Gene Therapy Research and Development, call us at 1-855-377-6821.